Designwala

Where Art meets Science and vice versa.

by Ria Rajan

In simple words, Synthetic Biology is about making living organisms do things which nature had not intended on them doing. Its about taking tiny bits of DNA, splicing them together and inserting them into bacteria. In effect, a bacterium could be made to change colour or made to be bright enough to be visible to the naked eye. In Yashas Shetty’s words, Artist and faculty member at Srishti School of Art, Design and Technology as well as Artist-in-Residence at NCBS – National Centre for Biological Sciences (NCBS) – “this mixing and matching of elements to create new things was a bit like what artists did. But instead of using paints and canvas, synthetic biologists used life itself.”

This thoughtful insight by Yashas Shetty led him to mentor a bunch of art& design students – who knew very little, if anything about science to participate in the International Genetically Engineered Machine (iGEM) held at Massachusetts Institute of Technology (MIT) last year. One of the aims of the competition is to attempt to build simple biological systems from standard, interchangeable parts and operate them in living cells.

The iGEM competition facilitates this by providing a library of standardized parts (called BioBrick standard biological parts) to students, and asking them to design and build genetic machines with them. Student teams can also submit their own BioBricks. Successful projects produce cells that exhibit new and unusual properties by engineering sets of multiple genes together with mechanisms to regulate their expression.

Information about BioBrick standard biological parts, and a toolkit to make and manipulate them, is provided by the Registry of Standard Biological Parts, or simply, the Registry. This is a core resource for the iGEM program, and one that has been evolving rapidly to meet the needs of the program. Beyond just building biological systems, broader goals of iGEM include:

• To enable the systematic engineering of biology.
• To promote the open and transparent development of tools for engineering biology.
• To help construct a society that can productively apply biological technology.

As per the rules of the competition, MIT sends all participants 400 bits of DNA. They are all numbered. One cant go to a database of parts on the web and find out which DNA makes what and then make your organism in the laboratory using the DNA bits.

NCBS had been sending students for MIT’s iGem competition for the last couple of years. Last year they decided to send art students – who knew nothing about science – to participate instead. They were called the ArtScience Team from Bangalore. And, unlike scientists, the artists came up with a project which only artists could have thought of: they were going to replicate the smell of first rain in a laboratory— that odour when pure water from the skies mixes with soil.” The English word for the smell is Petrichor, a non-lyrical name for a phenomenon that is so emotive. The primary cause behind the smell, however, has a slightly more lyrical name: Geosmin, an organic chemical.

The students did the scientific parts in the laboratory of NCBS. At the end of it, Shetty says, the experiment didn’t turn out the smell of first rain. Instead there was this smell of dampness.

But it was enough.

They won the third prize for science. The presentation, in which they explained how a group of art students became scientists for a season, got them a special prize for best presentation. “They said that they started off as artists and are now talking to scientists. I think that impressed the judges,” says Mukund Thattai of NCBS, whose laboratory the art students had used for this experiment. The ArtScience Team took synthetic biology to new groups, running workshops to teach designers to build working DIY microscopes using webcams and ran creative workshops at a school for the urban poor. This idea of “human practices” – that is, exploring the ethical and social implications of the technology – was a new focus of last year. What made this team stand out from the rest was the fact that they looked at the field from a beginners perspective and climbed their way up to the knowledge filed and shared it with anyone who was interested. While the other teams were focusing on a problem-solution approach they were more interested in making the knowledge that iGEM was distributing as accessible and open source as possible. Their process- start to finish, complete with drawings was documented in a handbook that was printed at distributed at the competition. It’s no surprise that they ran out of copies. The handbook is available for free download at – http://hackteria.org/wiki/images/a/a1/Handbook.pdf

When I asked Neha Bhatt, member of the ArtScience team – about her first hand experience with synthetic biology and its processes, she said “ it was a real eye –opener. For me, the competition’s process opened up a whole new area I’d never known existed. The field of artists doing science and the boundaries b/w art and science being traversed.”

Apart from being instrumental in changing people’s perspective towards synthetic biology, the participation of students of art+design in an otherwise science competition, threw open many discussions; primarily that was access. Should Science as a field and practice remain inclusive or should it open its doors to creative practioners as well; to explore and create? There were those purists, of course, who simply did not take them seriously, for they believed that artist’s are those who draw the bio diagrams; and the main question that they were faced with was – ” So if  you guys being beginners can be given the authority to play around with real life, can anyone looking to harm society also not to do the same?”

They’re answer was simply that their project was an experiment to these questions.

Team ArtScience 2010 is all set to make another appearance at this year’s IGEM. Here’s wishing them all the best and one hopes that more such lines between seemingly disparate disciplines get blurred, norms get challenged, more knowledge gets shared and that perceptions are constantly altered.

The iGEM 2010 site –

http://2010.igem.org/Main_Page

The wiki of Team ArtScience Bangalore -

http://2009.igem.org/Team:ArtScienceBangalore